Indigestion is typically a symptom and not a cause, therefore the treatment depends upon resolving the underlying cause. If indigestion is caused by lifestyle habits, the prognosis is good. Prevention of the lifestyle cause can often resolve the symptoms. If indigestion is caused by medications, talk to your doctor about changing medications to ones that do not cause indigestion. Never stop taking a medication without the advice of your physician. If indigestion is caused by a disease or medical condition, the prognosis is varied and dependent upon the resolution of that condition. Some conditions such as ulcers, GORD, and gastritis respond readily to acid blocking medications such as proton pump inhibitors.
Conditions such as food poisoning or pregnancy are self-limited and symptoms should decrease over time. Hernias and gallstones, for example, usually require surgery, and the associated indigestion should resolve post-operatively. Other conditions are difficult to treat or do not respond well to medication such as pancreatitis, gastroparesis, depression, and cancer. Treatment of these conditions may involve several methods including lifestyle changes, medications, specialist care and/or surgery.